Abstract: A refractory copper oxide in Yunnan with high degree of oxidation，serious mudding，fine or uneven disseminated size of useful minerals，and coarse disseminated copper sulfide,etc. Technical condition tests for beneficiation are made by the principle of firstly floating copper sulphide minerals and then floating copper oxide minerals. The results show that for copper oxide minerals，the grading separation process can effectively resolve the sludge constantly circulating and accumulating problems during the whole flow-sheet. Through the closed circuit，copper sulfide concentrate with Cu grade of 21.43%，and recovery of 47.73%，copper oxide concentrate with Cu grade of 17.41% and recovery of 19.39%，are gained respectively. In total concentrates，Cu grade is 20.09% and Cu recovery is 67.12%.

Key words: Copper sulphide minerals, Copper Oxide minerals, Grading separation