Abstract: The silver-polymetallic ore in Zhejiang contains 153 g/t silver，0.29% copper，0.83% lead，1.41% zinc.Copper，lead，and zinc exist mainly in form of sulfide.Main valuable minerals，chalcopyrite，galenite，sphalerite，and dalarnite keep closely intergrowth with each other in uneven grain size and irregular shape.In order to high efficiently utilize the ore，beneficiation experiment was carried out based on the process mineralogy.The experiment results indicated that：at the grinding fineness of 91.4% passing 0.045 mm，and by adopting the process of copper-lead bulk flotation with one roughing-four cleaning-one scavenging，rough concentrate through one roughing-two cleaning-two scavenging lead depressing and copper floating，rough tailings through one roughing-four cleaning-two scavenging operation，and middles back to the flow-sheet in turn，copper concentrate with copper grade of 22.47%，silver grade of 1 373 g/t，copper recovery of 69.08%，silver recovery of 8.02%，lead concentrate with lead grade of 40.63%，silver grade of 6 585 g/t，lead recovery of 81.14%，silver recovery of 71.64%，and zinc concentrate with zinc grade of 41.72%，silver grade of 197 g/t，zinc recovery of 79.85%，silver recovery of 3.48% were obtained respectively.This experimental closed circuit process is high efficient in the development and utilization of the ore.

Key words: Silver polymetallic ore, Copper-lead bulk flotation, Lead depressing and copper floating, Copper separation from lead