Abstract: The optimization of production and hauling dispatching in open-pit mine features as typical multivariate and nonlinearity.First of all，based on analysis on the optimization of the open-pit truck dispatching，with the minimum total transportation cost as the objective function，the quantity of ore and transport capacity as constraints，the transport dispatching optimization model was established，and then it was put forward that the local search function within differential algorithm was introduced into the improved biogeography-based optimization algorithm with migration strategy.Finally，with MATLAB software as a platform，and the actual production and transportation data in open-pit mine as the basis，the comprehensive transportation cost calculated from the improved biogeography algorithm save 59.94 million yuan than the actual costs.Moreover，the algorithm can lower the transport costs compared with the single biogeography and the differential algorithm，which verifies its superiority for solving transportation dispatching problem in open-pit mine.

Key words: Open-pit mine, Hauling dispatching, Biogeography-based algorithm, Optimization