Abstract: As a sort of widely used material in mining construction,the clay-cement slurry grouting has low seepage and filtration resistance at the initial reinforcement stage. The grouting reinforcement is affected because of its low strength and brittle damage. In order to prepared the new clay-cement slurry,graphene oxide( hGO) is selected to blend with the common claycement paste,which is prepared by Hummers method as a modifier. Based on the comparative analysis of the main performance parameters of hGO modified clay-cement slurry,including viscosity,stability,plastic strength and mechanical properties,under differences hGO incorporation by means of indoor tests and combined with the mechanism of hGO from microscopic morphological point of view employed scanning electron microscope experiment,the growth model of hGO modified clay-cement slurry nodules is proposed. The results show that:A spatial skeleton of clay-cement slurry body with hGO lamellae as the core and filled by clay particles is formed,which explains hGO modified clay-cement slurry performs better than traditional clay-cement slurry. With the increase of hGO admixture,the viscosity of clay-cement slurry increases by 163% at most. The stability and plastic strength of the modified clay-cement slurry are significantly enhanced,and the maximum of plastic strength is 7. 11 times under the same maintenance time. The early impermeability and water plugging of the slurry are significantly improved. The uniaxial compressive strength and shear strength of the plasma stone body are increased by 23. 94% and 25. 27%,which has obvious effects on the optimization of slurry durability.