Abstract: The mineral composition and structure of a refractory oxide copper in Sichuan is complex while the total copper of 93.79% are free copper oxide and combined copper oxide. These copper oxide exists in the form of malachite and azurite with fine dissemination and mainly distributes in the non-metallic mineral fractures. The technical conditioning tests for this ore indicated that the combination of DZ-602 and Na2S can effectively activate the oxidized copper minerals and increase its hydrophobic property. By adopting the process of two roughings,two cleanings,and two scavenings and middles back to the flowsheet in turn，copper concentrate with copper grade of 20.12% and copper recovery of 75.35% was obtained.

Key words: Refractory copper oxide ore, Malachite, Azurite, Efficient activator DZ-602