Abstract: Xiaochangba lead-zinc ore in Gansu belongs to the primary sulfide lead-zinc ore. As the main lead mineral，galena is closely disseminated with sphalerite,difficult to libevate，and unsatisfactory recovery of micro-fine particles are the main factor resulting in low recovery of lead. Taking D102 as collector for lead floating，and adopting the process of the preferential lead flotation with one roughing-two scavengings-three cleanings，and zinc floatation with one roughing-two scavengings-three cleanings，lead concentrate with Pb grade of 59.72% and recovery of 73.52%，and Zn content of 14.56%,and zinc concentrate with Zn grade of 52.97% and the recovery rate of 92.12% and Pb content of 1.60% were gained separately. With zinc recovery slightly increased,the percentage of lead recovery is improved 2.04%.

Key words: Lead-zinc ore, Dissemination of lead-zinc ore, D102, Zinc inhibiting and lead flotation