Abstract: For the deep stope in a high-stress environment of Hongtoushan Copper Mine，the rational mining sequence is discussed to ensure the stope stability during mining process by numerical simulation.Based on actual production conditions in the mine，six kinds of mining schemes are proposed，and FLAC3D is used to analyze the stress and displacement distribution at different mining schemes.The results show that：Scheme 6 is in the most favorable stress environment with maximum security，and the pillar obviously plays a role in releasing the stress concentration of roof.The roof and the wall are the most concentrated area of stress.The vertical displacement of scheme 2 in mining process is the minimum.However，six schemes have a closer final displacement state.Taking comprehensive consideration，the scheme 6 is the optimal mining sequence.

Key words: Deep stope, Mining sequence, Numerical simulation, Stope stability