Abstract: n order to explore the variation characteristics of the transport resistance of cemented paste backfill (CPB) slurry under the influence of wall slip effect，a pipeline transportation model considering the effect of wall slip was established，and the influence of slurry concentration，pipe diameter and ash-sand ratio on pipeline resistance loss was analyzed by using Comsol numerical simulation software.The study shows that:① The relative error of the simulation results is within a reasonable range，and the model is used to calculate the resistance of the filling slurry pipeline by considering the wall slip effect is reliable；② Considering the wall slip effect，order of the influence degree of each factor on the pipe resistance is the pipe diameter，mass concentration and lime sand ratio，the pipe diameter is increased，the wall shearing force is reduced， and the migration movement of the particles is slower and slipper，the shift effect is weakened，and the decrease in the resistance of the pipeline is reduced；③ The main controlling factors of the thickness of the slurry slip layer in different concentration ranges are different，which leads to different amplitudes of transport resistance increase with concentration；④ When the cement to tailings ratio relatively low， the growth rate of the pipeline transportation resistance is low，as the cement to tailings ratio increases，the pipeline transportation resistance increases rapidly.Numerical simulation was carried out with a mine in Eastern Hebei Province as the study background，and the best parameters for pipeline transportation of filler slurry are determined as concentration 66%，68% ，and the cement-sand ratio is 1∶8.

Key words: filling mining, wall slippage, high concentration mortar, pipeline transportation, resistance loss