Abstract: In order to compare the influence of ceramic medium and cast iron medium stirring grinding on the leaching effect of gold in cyanide tailings,the gold leaching tailings of China Gold Group Sanhe Gold Industry Co. ,Ltd. were taken as the research object,and the gold leaching experiment was carried out. The research results show that the optimal process parameters in this experiment are grinding fineness of -6 μm accounting for 90%,dosage of JC leaching agent of 40 kg / t and leaching time of 12 h. Under the optimal process parameters,the technical indicators of leaching slag Au grade of 1. 29 g / t and leaching rate of 54. 45% can be obtained by using ceramic media grinding,and the technical indicators of leaching slag Au grade of 2. 15 g / t and leaching rate of 39. 45% can be obtained by using cast iron medium grinding. The leaching rate of gold under the condition of ceramic media grinding is significantly higher than that of traditional cast iron media grinding. After adding Fe³⁺ in the ceramic media grinding process,the leaching effect of gold was significantly decreased,indicating that the addition of Fe³⁺ was not conducive to the leaching of gold. Mechanism analysis shows that Fe³⁺ will be generated during the grinding process of cast iron medium,and Fe³⁺ will form iron oxyhydroxide (FeOOH) on the mineral surface,which hinders the diffusion process of CN^- and deteriorates the leaching environment,thereby reducing the leaching rate of gold.