Abstract: The stability of open pit slope is the key factor affecting the mine production security.Based on the results of field investigation，it shows that slope lithology，water，and mining disturbance are the main three factors affecting the stability of Mine.The slope is divided to three areas by comprehensively considering the slope stability of rock and earth mass and the reinforcement measures of whole-length bonding bolt，anchor wire technology，steel mesh+spray anchor net are taken to strengthen the slope stability.Based on the actual situation of the slope，some treatment measures are taken，such as full-length grouted bolt，pre-stressed cable，hanging shotcrete.Based on the pre-blasting technology theory，the pre-blasting parameter of the Yanshan Iron Mine was designed and brought into the field operations.The results show that the parameters greatly reduced blasting vibration and damage to the slope step，and then significantly improve the slope stability.The research lays a good foundation for the safety production of the mine.

Key words: Open-pit slope, Slope stability, Slope reinforcement, Pre-splitting blasting