Abstract: Jiangcangnan Pb-Zn deposit is located in the southern section of Tuotuo river area,which is the northern extension of Sanjiang polymetallic metallogenic belt in the northeastern margin of the Tibetan Plateau.Based on the field investigation，7 large-scale Pb-Zn geophysical anomalies are found and the strong Pb-Zn mineralization potential is presented in the research area.The further analysis results of the above geophysical anomalies show that:①the limestone in the Permian ninety team is the main surrounding rock with high contents of the elements such as Pb，Zn,etc;②the selected 7 mineralization zone mentioned above is located in the fracture development geological structure area，such as in the intersection of faults，unconformity interface of formation and so on，they are mainly NW-direction and nearly EW-direction,it indicated the evidence that one of the important controlling factors of Pb-Zn deposit is the geological structure in the research area;③the Pb grade is from 0.53% to 5.45%，the Zn grade is from 0.91% to 4.67% in the orebody of the Pb-Zn deposit,the Pb metal capacity is almost 1.45×105 t,it means that the metal ore deposit is the medium size and shows a good potential for exploring mineral resource.Based on analyzing the geological background of mineralization,ore deposit geological characteristics,orebody geological characteristics in the research area，the ore-controlling factors,ore deposit genesis and prospecting indicators in the research area are also studied in depth,it concluded that the Jiangcangnan Pb-Zn deposit is a middle-low-temperature hydrothermal deposit with the significantly structure controlling the oxide strips with the red，brown，gray and other colors in or nearby the fracture development geological structure area is the obvious sign of the development of Pb-Zn deposit.The above research results can provide the reference for the further exploration and exploitation work of the other Pb-Zn deposit in Tuotuo river area.

Key words: Geological characteristics, Orebody characteristics, Ore-controlling factors, Ore deposit genesis, Prospecting indicators, Prospecting direction, Pb-Zn deposit