Abstract: The content of pyrite in copper-zinc polymetallic sulfide ore in Hebei Province is high， and the relationship between copper and zinc minerals is closely and complicated. The content of copper， zinc and sulfur is 1.14%， 6.67% and 29.12%， and belongs to high sulfur copper-zinc ore. To provide basis for rational development and utilization of the ore， beneficiation experiment was conducted. Results show that， via one roughing one cleaning one scavenging copper flotation， one roughing one cleaning one scavenging of zinc flotation on copper tailings，one roughing one scavenging of sulfur flotation on zinc tailings， copper concentrate with copper grade of 24.13%，zinc content of 9.33% and copper recovery of 73.86%， zinc concentrate with zinc grade of 50.63%， copper content of 1.95%，and the zinc recovery of 91.01%， sulfur concentrate with sulfur grade of 53.34% and sulfur recovery of 74.46% was obtained. The experimental results can be used as the basis for the comprehensive development and utilization of the high sulfur copper-zinc ore.

Key words: High-sulfur copper-zinc ore, Preferential flotation, Copper-zinc separation, Comprehensive recovery