Abstract:  In order to realize the systematic engineering construction of gene mineral processing，the relationship between gene characteristics and flotation of copper ore was investigated，this paper takes the representative copper minerals chalcopyrite，bornite，malachite，chalcopyrite and chalcopyrite as the research object，and summarizes the gene characteristics of copper bearing minerals through XPS，solubility test，zeta potential，contact angle test analysis and MS calculation. The floatability of several copper minerals has been studied under natural condition. The natural floatability of copper minerals was obtained by flotation test as follows: bornite>chalcopyrite>>cuprite>malachite>azurite；In sodium ethyl xanthate （NaEX），sodium butyl xanthate（NaBX），isoamyl xanthate（NaIAX）and ammonium butyl aerofloat flotation of chalcopyrite，bornite has good flotability，with malachite and azurite and flotability of cuprite is poorer，general rule is: bornite>chalcopyrite>azurite≈malachite>cuprite.  The results show that the natural floatability of copper minerals is related to the genetic characteristics of fracture surface，fracture bond density and fracture bond，and the floatability of copper minerals is related to the genetic characteristics of band gap width and surface S element content under the flotation reagent of NaEX，NaBX，NaIAX and ammonium butyrate.

Key words: Copper minerals, Genetic mineral processing engineering, Floatability, Genetic characteristics, Crystal chemistry