Abstract: The relationship between the anisotropy of chlorite and its floatability was studied via X-ray diffraction （XRD）analysis，single mineral flotation，adsorption law of collector，and molecular dynamics simulation for three size fraction of chlorite（-37 μm，37~44 μm，44~74 μm）. The XRD analysis results indicated that the content of parallel cleavage plane increased continuously with the size fraction decrease，and interlamellar cleavage plane liberated preferentially. The flotation results demonstrated that the floatability order was medium size fraction（37-44 μm）>fine size fraction（-37 μm）> coarse size fraction（44-74 μm）. The adsorption law of dodecylamine and molecular dynamics simulation results confirmed that the adsorption density of dodecylamine on chlorite surface decreased with the decrease of size fraction，while the adsorption amount increased with the decrease of size fraction，and dodecylamine mostly adsorbed on chlorite（001）surface along the normal direction. Compared with（001）surface of chlorite，there are massive positive metal ions on（100）surface， which weaken the electrostatic adsorption effect of dodecylamine on（100）surface，resulting in the lower adsorption target degree of dodecylamine on chlorite（100）surface（ineffective adsorption）and the higher adsorption strength of dodecylamine on（001）surface than that of（100）surface. Chlorite shows anisotropy obviously and the increase of（001）surface content is favorable for chlorite flotation. Increasing the dissociation of interlayer efficiency via selective grinding is the key point of improving the effect of chlorite flotation. 

Key words: Chlorite, Anisotropy, Size fraction, Dodecylamine, Adsorption, Normal direction, Target degree