Abstract: The crystal structure and surface properties of spodumene and potassium feldspar were studied by means of quantum chemical calculation，X-ray photoelectron spectroscopy analysis，zeta potential measurement on mineral surfaces， single mineral flotation tests，etc. The relationship between minerals“Genetic Properties”and their floatability was investi? gated as well. The results show that the Li-O bond and Al-O bond in spodumene crystal structure are relatively easy to break，hence Li⁺，Al³⁺ metal ions tend to be liberated form the mineral surfaces，and the mineral has relatively high PZC， while the K-O bond and Si-O bond in potassium feldspar crystal structure are easy to break，the liberated mineral surfaces are easy to adsorb hydroxyl in water，which makes the surfaces have more negative charges，hence the PZC of feldspar is relatively low. The floatability of spodumene in anionic collection system is higher than that of feldspar，while the former is lower than the latter in cationic collection system. There exists a manifest relationship between the genetic properties of minerals and their floatability，which verifies that the research of genetic mineral processing engineering is significance for guiding the practice of mineral processing.

Key words: Spodumene, Potassium feldspar, Genetic properties, Floatability, Quantum chemical calculation