Abstract: An African weathered residual granite pegmatite niobium-tantalum ore contains Nb2O5 of 0. 011% and Ta2O5 of 0. 015% . Niobium and tantalum elements primarily reside in weakly magnetic minerals such as ferrocolumbite and manganotantalite. The ore exhibits intense kaolinization. In order to determine a suitable beneficiation testing procedure,systematic mineral processing investigations were conducted based on ore characteristics. Considering the low metallic mineral content,severe weathering,and high clay mineral content of the ore,a combined metallurgical process of " blunging,classification,grinding, low-intensity magnetic separation (LIMS),high-intensity magnetic separation (HIMS),classified shaking table,acid washing, and high-intensity magnetic separation (HIMS)" was established. The closed-circuit test achieved a niobium-tantalum concentrate assaying Nb2O5 of 26. 001% and Ta2O5 of 35. 713%,with recovery rates of 70. 03% for Nb2O5 and 69. 56% for Ta2O5 . The concentrate meets the requirements for Grade I products specified in the industry standard Tantalum Concentrates (YS / T 394—2007),providing technical support for the development of similar ore resources.