Abstract: Taking Na₂SiO₃，Na₂SO₃ and CMC as the combinatorial depressant, an experimental research on copper-lead separation from flotation concentrates for a copper-lead-zinc multi-metal sulfide mine was made.Such factors for the copper-lead separation as the consumption of the combinatorial depressant, pump density and time were studied to seek for an optimum condition.Based on this, the copper concentrate grading 27.19% and bearing 5.13% of lead at a 97.26% copper recovery and the lead concentrate grading 72.98% and bearing 1.46% of copper at an 88.08% recovery were obtained by a closed-circuit process of one-rough concentration, two-scavenger and two-cleaning separation. 

Key words: Copper-lead concentrate, Copper-lead separation, Combinatorial depressant