Abstract: Dachang ore field is a famous tin-polymetallic deposit in China with significant distribution rule on the plane and in vertical direction for ore deposit.The second ore-prospecting place，which is below the surface 600 meter，is of great potential in ore prospecting.Under the guide of modern metallogenic theory and metallogenic prognosis，various techniques and methods were integrated，including comprehensive geological study，trend surface analysis，and geophysics，geochemistry and remote sensing.Among them，the comprehensive geological study could determine the ore prospecting space，and the variation of geologic body and the vertical space of ore-body could be got by the trend surface analysis.The technique of geophysics，geochemistry，remote sensing provided the three-dimensional space prospecting information.The mineralization prognosis in Heishuigou-tongkeng deep area in Dachang ore field is remarkably made with good results achieved.After prognosis verification，the new Zn-polymetallic resources are close to a super large deposit.  

Key words: Various technique and method, Mineralization prognosis, Heishuigou-tongkeng area, Dachang ore field