Abstract: In view of characteristics of complex ore components，and easily-floation but hard-separation of valuable minerals for a silver-tin poly-metallic sulfide ore，the beneficiation tests were carried out by the process of zinc-tin mixing flotation- copper-lead flotation of mixing concentrate-zinc-sulfur flotation of mixing tailing with new-type special collector EMS-01A，and then copper，lead，zinc，silver and sulfur were recycled successfully.The reaction mechanism between EMS-01A and the target minerals was investigated by Zeta-potential tests and IR spectrum analysis，which indicates that the chemical adsorption is realized strongly on chalcopyrite and galena surface by EMS-01A while the absorption on sphalerite and pyrite was comparatively weak.This provides a guarantee for separation of Cu-Pb and S-Zn.

Key words: Poly-metallic sulfide ore, Floatation, New type collector EMS-01A, Zeta-potential tests, IR spectrum analysis