Abstract: A Nickele-Molybdenum Ore in Zhangjiajie was reasearched，focusing on grinding fineness in single-stage grinding and flotation reagent system of roughing.The grinding and flotation flowsheet was introduced.A closed circuit test was carried out by the production of rough grinding floated by two roughing and three cleaning，the intermediate concentrate of regrinding production floated by two cleaning and middlings returned in order.The flotation concentration containing 2.21% of Mo with molybdenum recovery of 84.53% was obtained.Phosphorite contained the flotation concentration was dissolved by hydrochloric acid，then the grade and recovery of Mo concentration could reach to 5.73% and 93.34% respectively.

Key words: Nickele-Molybdenum Ore, Flotation, Regrinding