Abstract: Based on the process mineralogy research,the technical conditions for the mixed flotation of a lead-antimony-silver polymeatllic native ore were investigated. Through experimental research，mixed concentrate with the grade of Sb 28.00%，Pb 31.00%，Ag 920.0 g/t and the recovery of Pb 85.69%，Sb 95.89%，Ag 78.39% was obtained under the condition of crude ore grinding to -0.074 mm 85% and by the process of a roughing-two scavenging-three cleaning and middlings returned into the flow process orderly.

Key words: Lead-antimony-silver polymetallic mine, Symbiotic ore of Lead-antimony-silver, Mixed Flotation