Abstract: The cementation and discharging process of tailings has become a new way of tailings processing in China.Taking full tailings slurry mixed with cement from an iron ore in Anhui as the experimental materials，by adopting the orthogonal design method and the extremum difference analysis method，the influence of weight concentration，cement-tailings ratio and cementitious materials on settlement characteristics are studied and contrasted.The experimental results show that among three factors of weight concentration，cement-tailings ratio and cementitious materials，the weight concentration has a maximum effect，followed by cementitious materials and cement-failings ratio in order.That is，the effect of weight concentration on the slurry settlement characteristics is most significant.In the experiment，under the condition of the concentration 78%，the cement-failings ratio 8%，and the cementitious materials type of TC-II，both the settlement and the sedimentation velocity of the full tailings slurry mixed with cement are minimal.So the final formula with the slurry concentration of 75%~78%，cement-failings ratio of 8% and cementitious materials of TC-II is recommended.

Key words: Tailings cementation, Full tailings slurry mixed with cement, Orthogonal test, Settlement characteristics