Abstract: Taking the Gaerqiong-Glalae Cu-Au ore-concentrated area as the research object，the S and Pb isotope compositions characteristics of sulfide ore and the metallogenic material sources are analyzed.The results show that:①the δ34S value of the ore metal sulfides vary from -4.4‰ to 6.2‰，with the average δ34S value of 0.13‰，mainly between -2 ‰ and 1.5 ‰，and with the characteristics of tower distribution,it overall reflects the characteristics of mantle magma sulfur，but has been contaminated by a few of crustal sulfur;②the composition range of Pb isotope of the ore is large，showing the characteristics of mixed source of lead,the characteristics of μ value and tectonic environment discrimination diagram indicate that lead of the research region is originated in the mantle source region，mainly the upper crust and mantle mixed orogenic belt lead;③comparing with the Buza and Naruo deposit in Duolong ore-concentrated area and the Gaerqiong-Glalae Cu-Au ore-concentrated area，it is considered that the source of sulfur of the above ore-concentrated areas are both magmatic sulfur，and the ore-forming materials of Duolong ore-concentrated area is relatively deep with the environment of subduction，and the ore-forming materials of Gaerqiong-Galale ore-concentrated area is relatively shallow with the environment of collision.The above analysis results have a certain reference for the prospecting work in the research area.

Key words: S isotope, Pb isotope, Geochemical characteristics, Crust mantle mixed sources, Sources of ore-forming materials