Abstract: PZO is a new type of copper sulphide flotation collector which was invented by Guangzhou Research Institute of Non-ferrous Metals.In order to examine selectivity of PZO on chalcopyrite and pyrite separation，PZO，butyl xanthate and butyl ammonium aerofloat effect on single mineral flotation of chalcopyrite and pyrite were compared separately under the condition of different pulp pH value and dosage.Meanwhile，PZO in chalcopyrite and pyrite surface adsorption amount and mechanism were studied with UV-VIS spectrophotometer and infrared spectrometer.The results showed that，①In the test pH range，butyl xanthate and butyl ammonium aerofloat and PZO floatobility ability are stronger than the pyrite of chalcopyrite.②The influence of slurry pH value on chalcopyrite floatobility ability are smaller，and the high recovery rate of chalcopyrite among weak acid or alkaline conditions，the flotability of pyrite in acidic conditions is stronger than the alkali conditions.③Collector′s selective ability from stronger weaker are PZO>ammonium butyl aerofloat > butyl xanthate，When pH=8.5 chalcopyrite and pyrite recovery rate difference value can reach 68.19 percentage points.④PZO is an ester of flotation reagent，compared with pyrite，more easily adsorpted on chalcopyrite surface，and mainly belongs to chemisorption.The abrove results show that，under slurry pH 8.5 PZO can efficiently separate chalcopyrite and pyrite.

Key words: Chalcopyrite, Pyrite, Collector PZO, Selective, Adsorption, Chemisorption.