Abstract: The sulfur content of an iron concentrate in plant from Xinjiang is relatively high reaching 1.07%， which is significantly higher than the sulfur content of the raw materials in the furnace. Flotation test was carried out to determine the rational desulfurization process of iron concentrate. The results showed that FS was used as activator， isobutyl xanthate was used as collector， and 2# oil was used as foaming agent. The rough flotation dosage was 2 000，200，30 g/t， and cleaning flotation dosage is 500，100，20 g/t， respectively. The sample was treated with one roughing one cleaning closed circuit process， and finally iron concentrate with iron grade of 64.53%， iron recovery of 97.13%， and sulfur content of 0.21% was obtained. The quality requirement of sulfur content in iron concentrate has been achieved.

Key words: Iron Concentrate, Reverse flotation, Desulfurization, Activator