Abstract: There is 0.77% Pb，2.13% Zn in gold-silver bearing lead-zinc sulfide ore in Yunnan. There is a large amount of precious metals such as gold and silver. The gold and silver have fine grain size. In order to provide a basis for the development and utilization of the ore， the preferential flotation lead sulfide process and lead tailings and selection zinc was carried out. The results show that the fineness of grinding is -0.074 mm accounting for 81.33%， sodium carbonate as pH adjuster， zinc sulfate + sodium metabisulfite as inhibitor， and ethyl sulfide nitrogen +3418A as collector， via two roughing three cleaning one scavenging lead flotation， lead tailings with copper sulfate + ammonium chloride as activator， butyl xanthate as collector， via one roughing two cleaning one scavenging zinc flotation process， obtained the lead concentrate with lead grade of 50.36%， gold grade is 28.79 g/t， the silver grade is 965.47 g/t， the lead recovery rate is 82.41%， the gold recovery rate is 77.18%， and the silver recovery rate is 78.69%. The zinc concentrate with zinc grade of 41.21% and zinc recovery rate is 87.45%， which realizes efficient recovery of useful metals in the ore.

Key words: Gold-silver bearing lead-zinc ore, Preferential flotation, Compounding agent, Comprehensive recycling