Abstract: Wenduergetuo lead-zinc deposit in Inner Mongolia is located in the southwest part of Shamai tungsten metallogenic belt and the northeast part of the Oyute copper metallogenic belt.It is a newly discovered deposit in recent years which has been rarely involved.In order to deeply study the metallogenic regularity of the mining area，based on the newly prospecting results in this area，the metallogenic geological background，geochemical characteristics，geophysical characteristics and geological characteristics of deposits are studied.The results show that:①the lead-zinc orebodies are mainly controlled by the NE-trending and NW-trending fault structures in space，and the necessary channels for the movement and storage for mineral fluids are provided；②The orebodies are hosted Yanshanian adamellite，the adamellite provides the necessary thermal source and material for the formation of orebodies；③the ore is mainly in the form of scaly granular blastic texture，fine vein-star scattered disseminated structure and block structure，the distribution of sphalerite is characterized in a heterogeneous scattered pattern；④the orebodies are mostly distributed with banded shape，and a few are lenticular shape，with the phenomenons of branching and expansion and shrinkage；⑤the lead-zinc orebodies in this area is formed by the dissolution，replacement and extraction of underground hot water to form ore-bearing hydrothermal fluid，the ore-bearing hydrothermal fluid is further activated，removed and enriched by the later magmatic activity，and precipitates into ore at a suitable location.the lead-zinc deposit in this area belongs to the magmatic hydrothermal lead-zinc deposit.Based on the above discussion results，the favorable prospecting indicators are summarized，they are geological structures，magmatic activities，surrounding rock alteration，geochemical anomalies and polarizabilities anomalies，a integrated prospecting model for this area is established and five prospecting target areas are delineated.The B1，B2，B4 and B5 prospecting target areas are distributed on the F1 structural belt，which are connected end to end.The metallogenic geological background of the four areas are basically consistent with each other，and they are actually belongs a target area with large scale.The total length of the structural alteration zone in this target area is about 6.2 km，the average thickness of the four orebodies that have been circled is 3.16 m， extending more than 200 m downward，and the average content of zinc is 1.03％.The prospecting results further indicated that the metallogenic potential in the prospecting target areas is good，and they are worth conducting further prospecting work.

Key words: Lead-zinc deposit, Shamai tungsten metallogenic belt, Oyute copper metallogenic belt, Deposit geological characteristics, Integrated prospecting model, Prospecting indicator, Prospecting target area