Abstract: Pre-separation-wet extraction is the most potential development direction of vanadium extraction from stone coal. Vanadium in stone coal mainly exists in muscovite. Pre-separation mainly uses flotation method to separate vein minerals such as vanadium-bearing muscovite and quartz in stone coal. Therefore， dodecylamine， octadecylamine， LU-1 and LU-3 were used as cationic collectors to investigate their flotation effects on muscovite and quartz. The results show that the concentration of collector has a great influence on the flotation of muscovite， but has no obvious influence on quartz. Under acidic conditions， dodecylamine， octadecylamine and LU-1 have good collecting effect on muscovite， among which dodecylamine has the best collecting effect. Under weak alkaline condition， LU-3 has a good effect on quartz collection. In the pre-separation of vanadium extraction from stone coal， dodecylamine can be used as collector to flotation muscovite or LU-3 can be used as collector to flotation quartz under acidic or alkaline conditions. The separation of muscovite and quartz can improve the leaching grade of vanadium and reduce the amount of material entering leaching process， thus reducing the consumption of leaching agent. The process is conducive to reducing costs and improving vanadium recovery.

Key words: Muscovite, Quartz, Cationic collectors, Flotation