Abstract: Jiguanzui Cu-Au Deposit is located in the northwest corner of the Yangxin rock mass and the northeastern margin of the Jinniu volcanic rock basin in the southeastern ore-forming area of the Middle-Lower Yangtze River Fe-Cu-Au metallogenic belt，adjacent to the Tonglushan Cu-Fe （Au） deposit.Until now，four new orebodies of V#，VI#，VII# and VIII# dominated by VII# orebody were discovered continuously in the mining area， which shows that the deep part of the deposit has good prospecting potential.Taking Jiguanzui Cu-Au Deposit in the area as the study object，the deep VII# orebody was studied in detail，the main gold-bearing mineral pyrite in the orebody was analyzed in detail，and the deep mineralization of the deposit was preliminarily discussed.On the basis of field investigation and indoor microscope identification，the pyrite is divided into two generations （PyⅠ and PyⅡ）， PyⅡ as main carrier minerals of gold.Elemental analysis of pyrite shows that the mass fraction of Co，Ni，Cu，Zn and As in pyrite was generally higher，and the change range of w（Co）/w（Ni） ratio was from 0.02 to 9.26.PyI is formed by magma， and PyII is formed by sedimentation.The isotope analysis of sulfur isotope and lead shows that 34S has obvious tower effect and has the characteristics of magmatic hydrothermal genesis.Lead is a mixed source of crust and mantle，which indicated that the ore-forming material source is a mixed source of crust and mantle based on mantle.Based on the above discussion results，the deep metallogenic potential of the deposit is further studied.The results show that the deep mineralization of the deposit is dominated by VII# orebody，which is produced near the contact zone between the Yanshanian quartz diorite and the Triassic lower carbonate rock stratum， and is controlled by the contact zone structure.The discovery of VII# orebody in the deep of the Jiguanzui Deposit indicates that the deep metal deposits in this area have good prospecting prospects.

Key words: Cu-Au deposit, Pyrite, Deep metallogenic, Deposit genesis, Metallogenic material source