Abstract: A weathered Nd-Fe-P polymetallic ore in Africa is a weathered crust composite pyrochlore ore， which containing Nb2O5 0.62%， P2O5 8.28%， Fe 13.91%，with severe ore weathering and high mud content. According to the difference in specific gravity between the valuable minerals and the gangue minerals in the ore， gravity separation is used to realize the pre-enrichment of valuable minerals. According to magnetite has high magnetism， magnetite is recovered by low intensity magnetic separation. According to apatite and calcite have flotability difference， apatite and calcite are recovered by flotation. The ore is firstly gravited by spiral chute to remove the tailings with a yield of 73.61%. The gravity separation concentrate is ground to -0.074 mm accounting for 78%. Under the condition of magnetic field intensity of 0.45T， an iron concentrate with Fe grade of 61.69% and recovery rate of 38.83% can be obtained through the low intensity magnetic separation. The iron tailings use sodium carbonate as the regulator and GY10 as the collector， after one roughing two cleaning two scavenging phosphorus flotation， phosphorus concentrate with P2O5 grade of 37.59% and recovery of 47.88% is obtained. The tailings of the phosphorus separation are adjusted by SH and the GSC is the collector， the niobium concentrate with Nb2O5 grade of 37.56% and recovery of 65.73% is obtained by one roughing two cleaning two scavenging niobium flotation. The research results can provide a basis for the development and utilization of such weathered antimony ore.

Key words: Polymetallic ore, Niobium minerals, Iron minerals, Phosphorite minerals, Flotation