Abstract: Regarding the stone coal roasted without any additive from Hubei province as the research target，the impact of F-contained leaching agent A on acid leaching of vanadium was studied. The results showed that F- in F- contained leaching agent A can break Si—O bond and Al—O bond in muscovite crystal structure，destroy the mica structure，and clear the pores of vanadium-contained minerals，thus providing a convenience for the reaction of acid with silicoaluminophosphate minerals such as quartz and feldspar etc..，The addition of F- contained leaching agent can lower the ΔG of the reaction of muscovite on thermodynamics; On the view of macroscopic，it can greatly improve the leaching rate of vanadium. Under the optimum conditions，the leaching rate of vanadium reached 85.37% and increased by 28.04%，compared with vanadium leaching directly with sulfuric acid.

Key words: Stone coal, Acid leaching, F-containing leaching agent, Thermodynamics