Abstract: The northern three-river metallogenic belt that belongs to Zhongza-Zhongdian block in Yushu region，Qinghai province is one of the most important metallogenic belts in southern Qinghai province.Based on the previous research results，although it has already been proved that the northern three-river metallogenic belt possesses a lot of metallogenic facts，there is no valuable prospecting clue found in Zhongza-Zhongdian block till now.The regional geological investigation with 1∶50 000 scale in Yushu region，Qinghai province is carried out，and the data of geochemistry and geological mineral are collected systematically based on multiple methods，such as remote sensing，geology and chemical exploration.Based on comprehensive analysis on the data，it is found that the elements such as Au，Ag，Cu，Sb，Ni，Cr，Co are contained richly in the stream sediments in Zhongza-Zhongdian block.In particular，the two kinds of element combination characteristics (Cu-Cr-Ni-Co and Au-Ag-As-Sb) are presented in Ningduo formation，Changcheng-Jixian system，middle proterozoic group，which is consistent with the fracture development in the region as well as its geological features，such as the widely distributed basic and intermediate-acidic intrusion rocks and intermediate-basic volcanic rocks in structural fracture belt and the strong alteration etc.Combined with the newfound metallogenic facts above，it is considered that the mineralization geological condition of Zhongza-Zhongdian block in the northern three-river metallogenic belt is good，and the prospecting potential of copper-gold polymetallic deposit is great.

Key words: Zhongza-Zhongdian block, Northern three-river metallogenic belt, Mineralization geological characteristics, Copper-gold polymetallic deposit, Prospecting potential