Abstract: There is 21.83% manganese in a silica-calcia low grade manganese ore from Sichuan Province.Manganese is finely disseminated in the ore and easy to be sliming.To provide basis for the development of the ore，beneficiation experiment was conducted on the ore by pre-sliming-grinding-high intensity magnetic separation-regrinding-cationic reverse flotation-anionic direct flotation process.Results show that ore via pre-sliming and ground to 75% passing 0.075 mm，ground products mixed with slime and then via one roughing-one scavenging high intensity magnetic separation，high intensity magnetic concentrate with manganese grade of 25.23% and recovery of 85.92% was obtained，high intensity magnetic concentrate reground to 85.14% passing 0.074 mm，using sulfuric acid as pH regulator，dodecylamine as collector，via one roughing-two scavenging reverse flotation，reverse flotation concentrate was obtained with manganese grade of 28.86%，recovery of 78.57%，using Na₂CO₃ as pH regulator，sodium hexametaphosphate as depressor，GJBW as collector via one roughing-two scavenging direct flotation，direct flotation concentrate with manganese grade of 33.62%，recovery rate is 72.76% was obtained.Test results can provide technique reference for utilization of the silica-calcia manganese.

Key words: Silica-calcia manganese, Magnetic separation, Flotation